Professor Chris Murphy

T:  +61 2 9351 4128 F:  +61 2 9351 2813 F13 - Anderson Stuart Building The University of Sydney NSW 2006 Australia

• Competitive grants
• Publications

Current national competitive grants

Publications

2008

Venuto, L, Lindsay, L, Murphy, C. Moesin is involved in the cytoskeletal remodelling of rat decidual cells. Acta histochemica. 2008; :

Biazik, J, Thompson, M, Murphy, C. Claudin-5 is restricted to the tight junction region of uterine epithelial cells in the uterus of pregnant/gravid squamate reptiles. Anatomical record (Hoboken, N.J. : 2007). 2008; 291:547-56

Kaneko, Y, Lindsay, L, Murphy, C. Focal adhesions disassemble during early pregnancy in rat uterine epithelial cells. Reproduction, Fertility, and Development. 2008; 20:892-899

Parker, S, Lindsay, L, Herbert, J, Murphy, C, Thompson, M. Expression and localization of Ca(2+)-ATPase in the uterus during the reproductive cycle of king quail (Coturnix chinensis) and zebra finch (Poephila guttata). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2008; 149:30-5

2007

Biazik, J, Thompson, M, Murphy, C. The tight junctional protein occludin is found in the uterine epithelium of squamate reptiles. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 2007; 177:935-43

Thompson, M, Lindsay, L, Herbert, J, Murphy, C. Calcium ATPase expression in the oviducts of the skink, Lampropholis guichenoti. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2007; 147:1090-1094

Adams, S, Biazik, J, Stewart, R, Murphy, C, Thompson, M. Fundamentals of viviparity: Comparison of seasonal changes in the uterine epithelium of oviparous and viviparous Lerista bougainvillii (Squamata: Scincidae). Journal of morphology. 2007; 268:624-635

Slater, M, Cooper, M, Murphy, C. The cytoskeletal proteins alpha-actinin, Ezrin, and talin are De-expressed in endometriosis and endometrioid carcinoma compared with normal uterine epithelium. Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry. 2007; 15:170-174

Adams, S, Lui, S, Jones, S, Thompson, M, Murphy, C. Uterine epithelial changes during placentation in the viviparous skink Eulamprus tympanum. Journal of morphology. 2007; 268:385-400

Lindsay, L, Murphy, C. Aquaporins are upregulated in glandular epithelium at the time of implantation in the rat. Journal of molecular histology. 2007; 38:87-95

2006

Stewart, J, Thompson, M, Attaway, M, Herbert, J, Murphy, C. Of the chorioallantoic placentome and the omphalopleure of the placentotrophic lizard, Pseudemoia entrecasteauxii. Journal of Experimental Zoology Part a-Comparative Experimental Biology. 2006; 305A:883-889

Lindsay, L, Murphy, C. Redistribution of aquaporins 1 and 5 in the rat uterus is dependent on progesterone: a study with light and electron microscopy. Reproduction (Cambridge, England). 2006; 131:369-78

Thompson, M, Biazik, J, Lui, S, Adams, S, Murphy, C. Morphological and functional changes to the uterus of lizards with different placental complexities. Herpetological Monographs. 2006; 20:178–185

Slater, M, Murphy, C. Co-expression of interleukin-6 and human growth hormone in apparently normal prostate biopsies that ultimately progress to prostate cancer using low pH, high temperature antigen retrieval. Journal of molecular histology. 2006; 37:37-41

Slater, M, Cooper, M, Murphy, C. Human growth hormone and interleukin-6 are upregulated in endometriosis and endometrioid adenocarcinoma. Acta histochemica. 2006; 108:13-8

Preston, A, Lindsay, L, Murphy, C. Desmosomes in uterine epithelial cells decrease at the time of implantation: an ultrastructural and morphometric study. Journal of morphology. 2006; 267:103-8

Thompson, M, Biazik, J, Lui, S, Adams, S, Murphy, C. Morphological and functional changes to the uterus of lizards with different placental complexities. Herpetological monographs. 2006; 20:178-185

Herbert, J, Lindsay, L, Murphy, C, Thompson, M. Calcium transport across the uterine epithelium of pregnant lizards. Herpetological monographs. 2006; 20:205-211

Stewart, J, Thompson, M, Attaway, M, Herbert, J, Murphy, C. Uptake of dextran-FITC by epithelial cells of the chorioallantoic placentome and the omphalopleure of the placentotrophic lizard, Pseudemoia entrecasteauxii. Journal of Experimental Zoology Part a-Comparative Experimental Biology. 2006; 305A:883-889

2005

Simon, C, Oberye, J, Bellver, J, Vidal, C, Bosch, E, Horcajadas, J, Murphy, C, Adams, S, Riesewijk, A, Mannaerts, B, Pellicer, A. Similar endometrial development in oocyte donors treated with either high- or standard-dose GnRH antagonist compared to treatment with a GnRH agonist or in natural cycles. Human Reproduction. 2005; 20:3318-3327

Slater, M, Cooper, M, Watson, G, Murphy, C. Adehesion molecules in endometriosis and Endometrioid adenocarcinoma show altered expressions suggesting a commonality between these diseases. Journal of Histotechnology. 2005; 28:185-190

Adams, S, Biazik, J, Thompson, M, Murphy, C. Cyto-epitheliochorial placenta of the viviparous lizard Pseudemoia entrecasteauxii: a new placental morphotype. Journal of morphology. 2005; 264:264-76

Slater, M, Quagliotto, G, Cooper, M, Murphy, C. Endometriotic cells exhibit metaplastic change and oxidative DNA damage as well as decreased function, compared to normal endometrium. Journal of molecular histology. 2005; 36:257-63

Thomson, M, Herbert, J, Murphy, C, Thompson, M. HoxA10-like proteins in the viviparous lizard Eulamprus tympanum and the oviparous lizard Lampropholis guichenoti. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 2005; 142:123-127

2004

Adams, S, Hosie, M, Murphy, C, Thompson, M. Changes in oviductal morphology of the skink, Lampropholis guichenoti, associated with egg production. Journal of morphology. 2004; 262:536-44

Ilad, R, Fleming, S, Bebington, C, Murphy, C. Ubiquitin is associated with the survival of ectopic stromal cells in endometriosis. Reproductive biology and endocrinology [electronic resource] : RB&E. 2004; 2:69

Murphy, C. Uterine receptivity and the plasma membrane transformation. Cell research. 2004; 14:259-67

Adams, S, Terry, V, Hosie, M, Gayer, N, Murphy, C. Endometrial response to IVF hormonal manipulation: comparative analysis of menopausal, down regulated and natural cycles. Reproductive biology and endocrinology [electronic resource] : RB&E. 2004; 2:21

Murphy, C, Adams, S, thompson, M, Biazik, J, Herbert, J. Placental function in lizards. International Congress Series. 2004; 1275:218-225

Preston, A, Lindsay, L, Murphy, C. Progesterone treatment and the progress of early pregnancy reduce desmoglein 1&2 staining along the lateral plasma membrane in rat uterine epithelial cells. Acta histochemica. 2004; 106:345-51

Lindsay, L, Murphy, C. Redistribution of aquaporins in uterine epithelial cells at the time of implantation in the rat. Acta histochemica. 2004; 106:299-307

Lindsay, L, Murphy, C. Aquaporin-1 increases in the rat myometrium during early pregnancy. Journal of molecular histology. 2004; 35:75-9

Adams, S, Murphy, C. Ultrastructure of the endometrial epithelial response to IVF hormonal manipulation. Current Medical Literature Gynaecology and Obstetrics. 2004; 10:1-4

2003

Hosie, M, Adams, S, Thompson, M, Murphy, C. Viviparous lizard, Eulamprus tympanum, shows changes in the uterine surface epithelium during early pregnancy that are similar to the plasma membrane transformation of mammals. Journal of morphology. 2003; 258:346-57

Hosie, M, Terry, V, Murphy, C. Expression of glucosamine trisaccharides on the rat uterine surface is altered by clomiphene citrate. III. Relationship with implantation regimes and pregnancy. Acta Histochemica. 2003; 105 (4):329-338

Hosie, M, Terry, V, Murphy, C. Expression of glucosamine trisaccharides on the rat uterine surface is altered by clomiphene citrate. III. Relationship with implantation regimes and pregnancy. Acta histochemica. 2003; 105:329-38

Isaacs, J, Murphy, C. Ultrastructural localisation of Muc-1 on the plasma membrane of uterine epithelial cells. Acta histochemica. 2003; 105:239-43

2002

Adams, S, Gayer, N, Hosie, M, Murphy, C. Human uterodomes (pinopods) do not display pinocytotic function. Human reproduction (Oxford, England). 2002; 17:1980-6

Slater, M, Murphy, C, Barden, J. Purinergic receptor expression in the apical plasma membrane of rat uterine epithelial cells during implantation. Cell calcium. 2002; 31:201-7

Thompson, M, Stewart, J, Speake, B, Hosie, M, Murphy, C. Evolution of viviparity: what can Australian lizards tell us?. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2002; 131:631-43

Murphy, C, Shaw, T. The cytoskeleton of uterine epithelial and stromal cells. In: The Endometrium. London: Taylor & Francis 2002. p. 39-45.

Slater, M, Murphy, C, Barden, J. Tenascin, E-cadherin and P2X calcium channel receptor expression is increased during rat blastocyst implantation. The Histochemical journal. 2002; 34:13-9

Isaacs, J, Murphy, C. Heparin-binding EGF-like growth factor is seen on the extracellular surface of uterine epithelial cells only after the initial stages of blastocyst attachment. The Histochemical journal. 2002; 34:339-43

Png, F, Murphy, C. Cytoskeletal proteins in uterine epithelial cells only partially return to the pre-receptive state after the period of receptivity. Acta histochemica. 2002; 104:235-44

Orchard, M, Murphy, C. Alterations in tight junction molecules of uterine epithelial cells during early pregnancy in the rat. Acta histochemica. 2002; 104:149-55

Everitt, A, Kofod, M, Terry, V, Murphy, C, Shorey, C, Berry, G. Differences in muscle fiber growth in slow-twitch muscles of the forelimb and hindlimb of the rat: role of the pituitary and food intake. Growth, development, and aging : GDA. 2002; 66:79-93

2001

Niklaus, A, Murphy, C, Lop, A. Characteristics of the uterine luminal surface epithelium at preovulatory & preimplantation stages in the Marmoset monkey. Anatomical Record. 2001; 25:777-780

Adams, S, Gayer, N, Terry, V, Murphy, C. Manipulation of the follicular phase: Uterodomes and pregnancy - is there a correlation?. BMC Pregnancy & Childbirth. 2001; 175:325-328

Adams, S, Gayer, N, Terry, V, Murphy, C. Manipulation of the follicular phase: Uterodomes and pregnancy - is there a correlation?. BMC pregnancy and childbirth [electronic resource]. 2001; 1:2

Bucci, M, Murphy, C. Hormonal control of enzyme activity during the plasma membrane transformation of uterine epithelial cells. Cell biology international. 2001; 25:859-71

Adams, S, Murphy, C. A successful pregnancy following SEM fine tuning of hormonal priming. BMC pregnancy and childbirth [electronic resource]. 2001; 1:3

Slater, M, Delprado, W, Murphy, C, Barden, J. Detection of preneoplasia in histologically normal prostate biopsies. Prostate cancer and prostatic diseases. 2001; 4:92-96

2000

Hosie, M, Terry, V, Shaw, T, Dwarte, D, Murphy, C. Expression of glucosamine trisaccharides on the rat uterine surface is altered by clomiphene citrate. II. Combination with ovarian hormones. Acta histochemica. 2000; 102:309-21

Slater, M, Barden, J, Murphy, C. Changes in growth factor expression in the ageing prostate may disrupt epithelial-stromal homeostasis. The Histochemical Journal. 2000; 32 (6):357-364

Png, F, Murphy, C. Closure of the Uterine Lumen and the Plasma Membrane Transformation do not Require Blastocyst Implantation. European Journal of Morphology 2000. 2000; 38 (2):122-127

Slater, M, Barden, J, Murphy, C. Distributional changes of purinergic receptor subtypes (P2X 1-7) in uterine epithelial cells during early pregnancy. The Histochemical Journal. 2000; 32 (6):365-372

Murphy, C, Hosie, M, Thompson, M. The plasma membrane transformation facilitates pregnancy in both reptiles and mammals. Comparative Biochemistry and Physiology Part A. 2000; 127 (4):433-439

Slater, M, Murphy, C. Transforming growth factors (alpha) & (beta)-1 are co-expressed in the uterine epithelium during early pregnancy. Cell & Tissue Research. 2000; 300 (2):315-320

Slater, M, Barden, J, Murphy, C. Tyrosine kinase A, autonomic & transmitter receptors, but not innervation, are upregulated in the aging rat prostate. acta histochemica. 2000; 102 (4):427-438

Tassell, W, Slater, M, Barden, J, Murphy, C. Endometrial cell death during early pregnancy in the rat. The Histochemical Journal. 2000; 32 (6):373-379

Hosie, M, Terry, V, Shaw, T, Dwarte, D, Murphy, C. Expression of glucosamine trisaccharides on the rat uterine surface is altered by clomiphene citrate. II. Combination with ovarian hormones. Acta Histochemica. 2000; 102 (3):311-321

Murphy, C. Junctional barrier complexes undergo major alterations during the plasma membrane transformation of uterine epithelial cells. Human Reproduction 15 (Supplement 3). 2000; 15 suppl 3:182-188

Murphy, C. The plasma membrane transformation of uterine epithelial cells during pregnancy. Journal of Reproduction and Fertility Supplement. 2000; 55:23-28

Slater, M, Barden, J, Murphy, C. The purinergic calcium channels P2X 1,2,5,7 are down-regulated while P2X 3,4,6 are up-regulated during apoptosis in the ageing rat prostate. The Histochemical Journal. 2000; 32 (9):571-580

Murphy, C. Understanding the apical surface markers of uterine receptivity. Human Reproduction. 2000; 15 (12):2451-2454