Dr Rachel Codd
D06 - Blackburn Building
The University of Sydney NSW 2006 Australia |
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A chemical biology approach to drug design and development; chemical proteomics of bacterial iron uptake; EPR spectroscopy.
Current national competitive grants
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2009 |
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Affinity-based profiling of bacterial Fe(III)-siderophore receptors: design strategies for antibiotics and iron overload |
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| NHMRC Project Grants | $264,250 over 3 years |
2010
- Liu, J, Obando, D, Schipanski, L, Groebler, L, Witting, P, Kalinowski, D, Richardson, D, Codd, R. Conjugates of Desferrioxamine B (DFOB) with Derivatives of Adamantane or with Orally Available Chelators as Potential Agents for Treating Iron Overload. Journal of medicinal chemistry. 2010; 53:1370-82
2009
- Codd, R, Braich, N, Liu, J, Soe, C, Pakchung, A. Zn(II)-dependent histone deacetylase inhibitors: Suberoylanilide hydroxamic acid and trichostatin A. The international journal of biochemistry & cell biology. 2009; 41:736-9
- Levina, A, Codd, R, Lay, P. Chromium in Cancer and Dietary Supplements. In: High Resolution EPR: Applications to Metalloenzymes and Metals in Medicine. United States: Springer 2009. p. 551-579.
- Liu, J, Clegg, J, Codd, R. 2,5-Dioxopyrrolidin-1-yl adamantane-1-carboxylate. Acta Crystallographica. Section E: Structure Reports Online. 2009; E65:o1742-o1743
- Liu, J, Clegg, J, Codd, R. Methyl 3-[(1-adamantatanylcarbonyloxy)aminocarbonyl]propanoate. Acta Crystallographica. Section E: Structure Reports Online. 2009; E65:o1742-o1743
2008
- Pakchung, A, Soe, C, Codd, R. Studies of Iron-Uptake Mechanisms in Two Bacterial Species of the Shewanella Genus Adapted to Middle-Range (Shewanella putrefaciens) or Antarctic (Shewanella gelidimarina) Temperatures. Chemistry & biodiversity. 2008; 5:2113-23
- Braich, N, Codd, R. Immobilised metal affinity chromatography for the capture of hydroxamate-containing siderophores and other Fe(iii)-binding metabolites directly from bacterial culture supernatants. The Analyst. 2008; 133:877-880
- Codd, R. Traversing the coordination chemistry and chemical biology of hydroxamic acids. Coordination Chemistry Reviews. 2008; 252:1387-1408
2006
- Codd, R, Lay, P, Tsibakhashvili, N, Kalabegishvili, T, Murusidze, I, Holman, H. Chromium(V) complexes generated in Arthrobacter oxydans by simulation analysis of EPR spectra. Journal of inorganic biochemistry. 2006; 100:1827-33
- Pakchung, A, Simpson, P, Codd, R. Life on Earth. Extremophiles Continue to Move the Goal Posts. Environmental Chemistry. 2006; 3:77-93
- Fainerman-Melnikova, M, Clegg, J, Codd, R. Aqua[bis(2-pyridylmethyl)amine][chelidonato(1.5-)]copper(II) chelidonate(0.5-) monohydrate. Acta Crystallographica. Section E: Structure Reports Online. 2006; 62:m3582-m3584
2005
- Gez, S, Luxenhofer, R, Levina, A, Codd, R, Lay, P. Chromium(V) complexes of hydroxamic acids: formation, structures, and reactivities. Inorganic Chemistry. 2005; 44:2934-2943
- Fainerman-Melnikova, M, Szabó-Plánka, T, Rockenbauer, A, Codd, R. Coordination modes between copper(II) and N-acetylneuraminic (sialic) acid from a 2D-simulation analysis of EPR spectra. Implications for copper mediation of sialoglycoconjugate chemistry relevant to human biology. Inorganic Chemistry. 2005; 44:2531-2543
2004
- Codd, R. Metalloglycomics: a new perspective upon competitive metal-carbohydrate binding using EPR spectroscopy. Chemical Communications. 2004; 0:2653-2655
- Levina, A, Codd, R, Foran, G, Hambley, T, Maschmeyer, T, Masters, A, Lay, P. X-ray absorption spectroscopic studies of chromium(V/IV/III)- 2-ethyl-2-hydroxybutanoato(2-/1-) complexes. Inorganic chemistry. 2004; 43:1046-1055
2003
- Codd, R, Lay, P. Oxochromium(V) species formed with 2,3-dehydro-2-deoxy-N-acetylneuraminic or N-acetylneuraminic (sialic) acids: an in vitro model system of oxochromium(V) species potentially stabilized in the respiratory tract upon inhalation of carcinogenic chromium(VI) compounds. Chemical research in toxicology. 2003; 16:881-892
- Codd, R, Irwin, J, Lay, P. Sialoglycoprotein and carbohydrate complexes in chromium toxicity. Current Opinion in Chemical Biology. 2003; 7:213-219
- Codd, R. Biomolcules from Extremophilic Life. In: From Zero to Infinity. Australia: University of Sydney 2003. p. 37-48.
- Levina, A, Codd, R, Dillon, C, Lay, P. Chromium in biology: Toxicology and nutritional aspects. Progress in Inorganic Chemistry. 2003; 51:145-250
2002
- Codd, R, Astashkin, A, Pacheco, A, Raitsimring, A, Enemark, J. Pulsed ELDOR spectroscopy of the Mo(V)/Fe(III) state of sulfite oxidase prepared by one-electron reduction with Ti(III) citrate. Journal of Biological Inorganic Chemistry. 2002; 7:338-350
2001
- Codd, R, Lay, P. Chromium(V)-sialic (neuraminic) acid species are formed from mixtures of chromium(VI) and saliva. Journal of the American Chemical Society. 2001; 123:11799-11800




