Associate Professor Chris O'Neill
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E25 - Royal North Shore Hospital
The University of Sydney NSW 2006 Australia |
Current national competitive grants
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2008 |
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The role of transcription factors in regulating the first round of gene expression in the early embryo |
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| NHMRC Project Grant | $334,875 over 3 years |
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Mechanisms of p53 induced embryopathy after in vitro fertilisation |
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| NHMRC Project Grant | $464,250 over 3 years |
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2007 |
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Development of a non invasive diagnostic test of Embryo Viability |
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| ARC Linkage Projects | $120,000 over 4 years |
2010
- Jin, X, O'Neill, C. The Presence and Activation of Two Essential Transcription Factors (cAMP Response Element-Binding Protein and cAMP-Dependent Transcription Factor ATF1) in the Two-Cell Mouse Embryo. Biology of reproduction. 2010; 82:459-68
2009
- Li, Y, O'Neill, C, Day, M. Activation of a Chloride Channel by a Trophic Ligand Is Required for Development of the Mouse Preimplantation Embryo In Vitro. Biology of reproduction. 2009; 81:759-67
- Jin, X, Chandrakanthan, V, Morgan, H, O'Neill, C. Preimplantation embryo development in the mouse requires the latency of TRP53 expression, which is induced by a ligand-activated PI3 kinase/AKT/MDM2-mediated signaling pathway. Biology of reproduction. 2009; 80:286-294
2008
- Morgan, H, Jin, X, Li, A, Whitelaw, E, O'Neill, C. The culture of zygotes to the blastocyst stage changes the postnatal expression of an epigentically labile allele, agouti viable yellow, in mice. Biology of reproduction. 2008; 79:618-623
2007
- Li, Y, Chandrakanthan, V, Day, M, O'Neill, C. Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo. Biology of reproduction. 2007; 77:813-821
- Mahsoudi, B, Li, A, O'Neill, C. Assessment of the long-term and transgenerational consequences of perturbing preimplantation embryo development in mice. Biology of reproduction. 2007; 77:889-896
- Jin, X, O'Neill, C. cAMP-responsive element-binding protein expression and regulation in the mouse preimplantation embryo. Reproduction (Cambridge, England). 2007; 134:667-675
- Li, Y, Day, M, O'neill, C. Autocrine activation of ion currents in the two-cell mouse embryo. Experimental cell research. 2007; 313:2786-94
- Li, A, Chandrakanthan, V, Chami, O, O'Neill, C. Culture of zygotes increases p53 expression in B6 mouse embryos, which reduces embryo viability. Biology of reproduction. 2007; 76:362-367
2006
- Chandrakanthan, V, Li, A, Chami, O, O'neill, C. Effects of in vitro fertilization and embryo culture on TRP53 and Bax expression in B6 mouse embryos. Reproductive biology and endocrinology [electronic resource] : RB&E. 2006; 4:61
2005
- O'Neill, C. The role of paf in embryo physiology. Human Reproduction Update. 2005; 11:215-28
2004
- Chami, O, Evans, G, O'Neill, C. Components of a platelet-activating factor-signaling loop are assembled in the ovine endometrium late in the estrous cycle. American journal of physiology. Endocrinology and metabolism. 2004; 287:E233-40
- Lu, D, Chandrakanthan, V, Cahana, A, Ishii, S, O'Neill, C. Trophic signals acting via phosphatidylinositol-3 kinase are required for normal pre-implantation mouse embryo development. Journal of cell science. 2004; 117:1567-76
2003
- Cahana, A, Jin, X, Reiner, O, Wynshaw-Boris, A, O'Neill, C. A study of the nature of embryonic lethality in LIS1-/- mice. Molecular reproduction and development. 2003; 66:134-142
- Lu, D, Li, Y, Bathgate, R, Day, M, O'Neill, C. Ligand-activated signal transduction in the 2-cell embryo. Biology of reproduction. 2003; 69:106-16
- Green, J, Waters, E, Haikerwal, A, O'neill, C, Raman, S, Booth, M, Gibbons, K. Social, cultural and environmental influences on child activity and eating in Australian migrant communities. Child Care Health And Development. 2003; 29 (6):441-448
2002
- Lu, D, Tian, L, O'Neill, C, King, N. Regulation of cellular adhesion molecule expression in murine oocytes, peri-implantation and post-implantation embryos. Cell Research. 2002; 12:373-383
2001
- O'Neill, C, Stojanov, T. In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice. Biology of Reproduction. 2001; 15:50-56
- Stojanov, T, Chami, O, Ishi, S, Shimuzu, T, Li, A, O'Neill, C, Wu, C, Stocker, R. Evidence of the Autocrine induction of capacitation of mammalian spermatozoa. Journal of Biological Chemistry. 2001; 19 (suppl 4):S21-S28
2000
- Cook, D, Stojanov, T, O'Neill, C, Emerson, M, Harding, E, Travis, A, Bathgate, R, Lu, D. Characterization and functional significance of calcium transients in the 2-cell mouse embryo induced bu an autocrine growth factor. Journal of Biological Chemistry. 2000; 275:21905-21913
