Dr Stuart Cordwell
G08 - Biochemistry Building
The University of Sydney NSW 2006 Australia |
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Our group is primarily interested in utilizing the tools of proteomics to understand disease processes and discover new targets for protein-based diagnosis of disease and potential vaccine and therapeutic targets.
Current national competitive grants
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2010 |
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Identification of proteins specific to transmissible Pseudomonas aeruginosa in cystic fibrosis infection |
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| NHMRC Project Grant | $427,200 over 3 years |
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2009 |
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Identification and analysis of novel replication initiation factors in Staphlylococcus aureus |
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| NHMRC Project Grant | $299,500 over 3 years |
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A temporal profile of signalling via phosphorylation during myocardial ischemia / reperfusion injury |
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| NHMRC Project Grants | $355,050 over 3 years |
2010
- Scott, N, Parker, B, Connolly, A, Paulech, J, Edwards, A, Crossett, B, Falconer, L, Kolarich, D, Djordjevic, S, Hojrup, P, Packer, N, Larsen, M, Cordwell, S. Simultaneous glycan-peptide characterization using hydrophilic interaction chromatography and parallel fragmentation by CID, HCD and ETD-MS applied to the N-linked glycoproteome of Campylobacter jejuni. Molecular & cellular proteomics : MCP. 2010; :
- Cordwell, S, Thingholm, T. Technologies for plasma membrane proteomics. Proteomics. 2010; 10:611-27
- Scott, N, Marzook, N, Deutscher, A, Falconer, L, Crossett, B, Djordjevic, S, Cordwell, S. Mass spectrometric characterization of the Campylobacter jejuni adherence factor CadF reveals post-translational processing that removes immunogenicity while retaining fibronectin binding. Proteomics. 2010; 10:277-88
2009
- Scott, N, Bogema, D, Connolly, A, Falconer, L, Djordjevic, S, Cordwell, S. Mass spectrometric characterization of the surface-associated 42 kDa lipoprotein JlpA as a glycosylated antigen in strains of Campylobacter jejuni. Journal of proteome research. 2009; 8:4654-64
- Faulkner, C, Blackman, L, Collings, D, Cordwell, S, Overall, R. Anti-tropomyosin antibodies co-localise with actin microfilaments and label plasmodesmata. European journal of cell biology. 2009; 88:357-69
- Scott, N, Cordwell, S. Campylobacter proteomics: guidelines, challenges and future perspectives. Expert review of proteomics. 2009; 6:61-74
- Wilton, J, Jenkins, C, Cordwell, S, Falconer, L, Minion, F, Oneal, D, Djordjevic, M, Connolly, A, Barchia, I, Walker, M, Djordjevic, S. Mhp493 (P216) is a proteolytically processed, cilium and heparin binding protein of Mycoplasma hyopneumoniae. Molecular microbiology. 2009; 71:566-82
- Lo, M, Cordwell, S, Bulach, D, Adler, B. Comparative transcriptional and translational analysis of leptospiral outer membrane protein expression in response to temperature. PLoS neglected tropical diseases. 2009; 3:e560
2008
- Upritchard, H, Cordwell, S, Lamont, I. Immunoproteomics to examine cystic fibrosis host interactions with extracellular Pseudomonas aeruginosa proteins. Infection and immunity. 2008; 76:4624-32
- Edwards, A, White, M, Cordwell, S. The role of proteomics in clinical cardiovascular biomarker discovery. Molecular & cellular proteomics : MCP. 2008; 7:1824-37
- Crossett, B, Edwards, A, White, M, Cordwell, S. Statistical Analysis of Image Data Provided by Two-Dimensional Gel Electrophoresis for Discovery Proteomics. In: Methods in Molecular Medicine: Clinical Bioinformatics. New Jersey, USA: Humana Press 2008. p. 271-285.
- Cordwell, S, Len, A, Touma, R, Scott, N, Falconer, L, Jones, D, Connolly, A, Crossett, B, Djordjevic, S. Identification of membrane-associated proteins from Campylobacter jejuni strains using complementary proteomics technologies. Proteomics. 2008; 8:122-39
- Cordwell, S. Sequential extraction of proteins by chemical reagents. Methods in molecular biology (Clifton, N.J.). 2008; 424:139-46
- White, M, Edwards, A, Cordwell, S, Van Eyk, J. Mitochondria: A mirror into cellular dysfunction in heart disease. Proteomics - Clinical Applications. 2008; 2:845-861
- Cordwell, S, Crossett, B, White, M. Gel-Based Approaches. In: Proteomics. Germany: Wiley - VCH Verlag GmbH & Co. KGaA 2008. p. 33-57.
2007
- Cole, J, Aquilina, J, Hains, P, Henningham, A, Sriprakash, K, Caparon, M, Nizet, V, Kotb, M, Cordwell, S, Djordjevic, S, Walker, M. Role of group A Streptococcus HtrA in the maturation of SpeB protease. Proteomics. 2007; 7:4488-98
- Henrich, S, Cordwell, S, Crossett, B, Baker, M, Christopherson, R. The nuclear proteome and DNA-binding fraction of human Raji lymphoma cells. Biochimica et biophysica acta. 2007; 1774:413-432
- Clark, D, Dedova, I, Cordwell, S, Matsumoto, I. Altered proteins of the anterior cingulate cortex white matter proteome in schizophrenia. PROTEOMICS CLINICAL APPLICATIONS. 2007; 1:157-166
- Harper, C, Cordwell, S, Alexander-Kaufman, K, Matsumoto, I. A proteome analysis of the dorsolateral prefrontal cortex in human alcoholic patients. PROTEOMICS CLINICAL APPLICATIONS. 2007; 1:62-72
- Sivagnanasundaram, S, Crossett, B, Dedova, I, Cordwell, S, Matsumoto, I. Abnormal pathways in the genu of the corpus callosum in schizophrenia pathogenesis: a proteome study. PROTEOMICS CLINICAL APPLICATIONS. 2007; 1:1291-1305
2006
- White, M, Tchen, A, McCarron, H, Hambly, B, Jeremy, R, Cordwell, S. Proteomics of ischemia and reperfusion injuries in rabbit myocardium with and without intervention by an oxygen-free radical scavenger. Proteomics. 2006; 6:6221-33
- Sivagnanasundaram, S, Caixeiro, N, Nesvaderani, M, Dedova, I, Cordwell, S, Matsumoto, I. Proteome profiling of the prefrontal cortex (PFC) and hippocampus of schizophrenia brains. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics. 2006; 141B:698-698
- O'brien, E, Dedova, I, Duffy, L, Cordwell, S, Karl, T, Matsumoto, I. Effects of chronic risperidone treatment on the striatal protein profiles in rats. Brain research. 2006; 1113:24-32
- White, M, Gundry, R, Cordwell, S. When does a fingerprint constitute a diagnostic?. Lancet. 2006; 368:971-973
- Caixeiro, N, Dedova, I, Cordwell, S, Matsumoto, I, Sivagnanasundaram, S. A proteomic analysis of Brodmann's area 46 (BA46) in schizophrenia. Australian and New Zealand Journal of Psychiatry. 2006; 40:A136-A136
- Nesvaderani, M, Dedova, I, Cordwell, S, Matsumoto, I, Sivagnanasundaram, S. Identification of proteins differentially expressed in the schizophrenic hippocampus. Australian and New Zealand Journal of Psychiatry. 2006; 40:A137-A137
- Sivagnanasundaram, S, Dedova, I, Cordwell, S, Matsumoto, I. Proteome analysis of the corpus callosum of schizophrenia. Australian and New Zealand Journal of Psychiatry. 2006; 40:A124-A124
- Cordwell, S. Technologies for bacterial surface proteomics. Current opinion in microbiology. 2006; 9:320-329
- White, M, Hambly, B, Jeremy, R, Cordwell, S. Ischemia-specific phosphorylation and myofilament translocation of heat shock protein 27 precedes alpha B-crystallin and occurs independently of reactive oxygen species in rabbit myocardium. Journal of molecular and cellular cardiology. 2006; 40:761-74
- Burnett, T, Dinkla, K, Rohde, M, Chhatwal, G, Uphoff, C, Srivastava, M, Cordwell, S, Geary, S, Liao, X, Minion, F, Walker, M, Djordjevic, S. P159 is a proteolytically processed, surface adhesin of Mycoplasma hyopneumoniae: defined domains of P159 bind heparin and promote adherence to eukaryote cells. Molecular Microbiology. 2006; 60:669-686
- Clark, D, Dedova, I, Cordwell, S, Matsumoto, I. A proteome analysis of the anterior cingulate cortex gray matter in schizophrenia. Molecular psychiatry. 2006; 11:459-70, 423
- Clark, D, Dedova, I, Cordwell, S, Matsumoto, I. Protein expression profile in the anterior cingulate cortex. Molecular psychiatry. 2006; 11:423
2005
- Hambly, B, White, M, Cordwell, S, Tchen, A, McCarron, H, Jeremy, R. Reversible ischemia/reperfusion injury correlates with troponin C modification. Biophysical Journal. 2005; 88:315A-315A
2003
- White, M, Cordwell, S, McCarron, H, Tchen, A, Hambly, B, Jeremy, R. Modifications of myosin-regulatory light chain correlate with function of stunned myocardium. Journal of molecular and cellular cardiology. 2003; 35:833-40




