Dr Emma Collinson
E:
T: +61 2 9036 3212
F: +61 2 9036 3038
Position
Postdoctoral Fellow
Qualifications/Employment
| 1997 | BSc (Hons). Biomedical Sciences (1997) University of Bradford, United Kingdom |
| 2000 | M.Med.Sci. Microbial Pathogenicity, University of Sheffield, United Kingdom |
| 2004 | PhD. Characterization of Yeast Glutaredoxins, University of Manchester, Institute of Science and Technology (UMIST) |
| 2004-2007 | Postdoctoral Fellow and Lecturer, School of Biotechnology and Biomolecular sciences, University of New South Wales, Sydney, Dawes Laboratory |
| Since 2007 | Postdoctoral Fellow, Centre for Vascular Resesarch, University of Sydney, Stocker Laboratory |
Characterization of the yeast homologue of HO-1, Hmx1p
Research tools
Yeast cellular and molecular biology
Collaborators
- Professor Ian Dawes, School of Biotechnology and Biomolecular sciences, University of New South Wales
PhD project
Cellular responses to adversity: oxidative stress and protection against oxidative damage in yeast
Research interests
Emma has worked in the area of oxidative stress for 7 years. She uses the model eukaryote S. cerevisiae as a tool to analyze cellular responses to oxidative stress. Much of the essential background research on antioxidant defense systems has been done in yeast. This is because S. cerevisiae can be genetically manipulated readily, and has a well-annotated genome sequence. Importantly, recent landmark studies in yeast have provided insight into the basis of complex diseases (e.g., Parkinsons Disease).
- Trotter EW, Collinson EJ, Dawes IW, Grant CM. Old yellow enzymes protect against acrolein toxicity in the yeast Saccharomyces cerevisiae. Appl Environ Microbiol. 2006 Jul;72(7):4885-92.
- Cipak A, Hasslacher M, Tehlivets O, Collinson EJ, Zivkovic M, Matijevic T, Wonisch W, Waeg G, Dawes IW, Zarkovic N, Kohlwein SD. Saccharomyces cerevisiae strain expressing a plant fatty acid desaturase produces polyunsaturated fatty acids and is susceptible to oxidative stress induced by lipid peroxidation. Free Radic Biol Med. 2006 Mar 1;40(5):897-906.
- Park JL, Collinson EJ, Grant CM, Dawes IW. Rom2p, the Rho1 GTP/GDP exchange factor of Saccharomyces cerevisiae, can mediate stress responses via the Ras-cAMP pathway. J Biol Chem. 2005 Jan 28;280(4):2529-35.
- Collinson EJ, Grant CM. Role of yeast glutaredoxins as glutathione S-transferases. J Biol Chem. 2003 Jun 20;278(25):22492-7.
- Collinson EJ, Wheeler GL, Garrido EO, Avery AM, Avery SV, Grant CM. The yeast glutaredoxins are active as glutathione peroxidases. J Biol Chem. 2002 May 10;277(19):16712-7.
