Dr Janette Kay Burgess

T:  9114 0368 F:  9114 0399 K26 Woolcock Institute of Medical Research The University of Sydney NSW 2006 Australia

• Research interests
• Competitive grants
• Publications

Research interests

Current national competitive grants

Publications

2010

Ge, Q, Moir, L, Black, J, Oliver, B, Burgess, J. TGFbeta1 induces IL-6 and inhibits IL-8 release in human bronchial epithelial cells-the role of SMAD2/3. Journal of cellular physiology. 2010; :

Lau, J, Oliver, B, Moir, L, Black, J, Burgess, J. Differential expression of peroxisome proliferator activated receptor gamma and cyclin D1 does not affect proliferation of asthma- and non-asthma-derived airway smooth muscle cells. Respirology. 2010; 15:303-312

Burgess, J, Boustany, S, Moir, L, Weckmann, M, Lau, J, Grafton, K, Baraket, M, Hansbro, P, Hansbro, N, Foster, P, Black, J, Oliver, B. Reduction of Tumstatin in Asthmatic Airways Contributes to Angiogenesis, Inflammation and Hyperresponsiveness. American journal of respiratory and critical care medicine. 2010; 181:106-15

2009

Ammit, A, Burgess, J, Hirst, S, Hughes, J, Kaur, M, Lau, J, Zuyderduyn, S. The effect of asthma therapeutics on signalling and transcriptional regulation of airway smooth muscle function. Pulmonary pharmacology & therapeutics. 2009; 22:446-54

Burgess, J, Ceresa, C, Johnson, S, Kanabar, V, Moir, L, Nguyen, T, Oliver, B, Schuliga, M, Ward, J. Tissue and matrix influences on airway smooth muscle function. Pulmonary pharmacology & therapeutics. 2009; 22:379-87

Bailey, S, Boustany, S, Burgess, J, Hirst, S, Sharma, H, Simcock, D, Suravaram, P, Weckmann, M. Airway vascular reactivity and vascularisation in human chronic airway disease. Pulmonary Pharmacology and Therapeutics. 2009; 22:417-425

Krimmer, D, Loseli, M, Hughes, J, Oliver, B, Moir, L, Hunt, N, Black, J, Burgess, J. CD40 and OX40 ligand are differentially regulated on asthmatic airway smooth muscle. Allergy. 2009; 64:1074-82

Fukuyama, S, Nakano, T, Matsumoto, T, Oliver, B, Burgess, J, Moriwaki, A, Tanaka, K, Kubo, M, Hoshino, T, Tanaka, H, McKenzie, A, Matsumoto, K, Aizawa, H, Nakanishi, Y, Yoshimura, A, Black, J, Inoue, H. Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype. American Journal of Respiratory and Critical Care Medicine. 2009; 179:992-998

Burgess, J. The role of the extracellular matrix and specific growth factors in the regulation of inflammation and remodelling in asthma. Pharmacology & Therapeutics. 2009; 122:19-29

2008

Burgess, J, Lee, J, Ge, Q, Ramsay, E, Poniris, M, Parmentier, J, Roth, M, Johnson, P, Hunt, N, Black, J, Ammit, A. Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: Differences in asthma. Journal of cellular physiology. 2008; 216:673-9

Zuyderduyn, S, Sukkar, M, Fust, A, Dhaliwal, S, Burgess, J. Treating asthma means treating airway smooth muscle cells. The European respiratory journal. 2008; 32:265-274

Hostettler, K, Roth, M, Burgess, J, Gencay, M, Gambazzi, F, Black, J, Tamm, M, Borger, P. Airway epithelium-derived transforming growth factor-beta is a regulator of fibroblast proliferation in both fibrotic and normal subjects. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2008; 38:1309-17

Oliver, B, Lim, S, Wark, P, Laza-Stanca, V, King, N, Black, J, Burgess, J, Roth, M, Johnston, S. Rhinovirus exposure impairs immune responses to bacterial products in human alveolar macrophages. Thorax. 2008; 63:519-25

Moir, L, Burgess, J, Black, J. Transforming growth factor beta(1) increases fibronectin deposition through integrin receptor alpha(5)beta(1) on human airway smooth muscle. The Journal of Allergy and Clinical Immunology. 2008; 121:1034-1039.e4

Black, J, Burgess, J, Oliver, B, Moir, L. Altered properties of airway smooth muscle in asthma. In: Airway Smooth Muscle in Asthma and COPD: Biology and Pharmacology. United Kingdom: John Wiley & Sons Ltd 2008. p. 181-199.

2007

Matsumoto, H, Moir, L, Oliver, B, Burgess, J, Roth, M, Black, J, McParland, B. Comparison of gel contraction mediated by asthmatic and non-asthmatic airway smooth muscle cells. Thorax. 2007; 62:848-54

Burgess, J, Moir, L. Airway remodeling: effect of current and future asthma therapies. Current Respiratory Medicine Reviews. 2007; 3:297-308

Borger, P, Matsumoto, H, Boustany, S, Gencay, M, Burgess, J, King, G, Black, J, Tamm, M, Roth, M. Disease-specific expression and regulation of CCAAT/enhancer-binding proteins in asthma and chronic obstructive pulmonary disease. The Journal of allergy and clinical immunology. 2007; 119:98-105

Ammit, A, Moir, L, Oliver, B, Hughes, J, Alkhouri, H, Ge, Q, Burgess, J, Black, J, Roth, M. The effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle. American journal of physiology. Lung cellular and molecular physiology. 2007; 292:L199-206

2006

Burgess, J, Oliver, B, Poniris, M, Ge, Q, Boustany, S, Cox, N, Moir, L, Johnson, P, Black, J. A phosphodiesterase 4 inhibitor inhibits matrix protein deposition in airways in vitro. The Journal of allergy and clinical immunology. 2006; 118:649-57

Chan, V, Burgess, J, Ratoff, J, O'Connor, B, Greenough, A, Lee, T, Hirst, S. Extracellular matrix regulates enhanced eotaxin expression in asthmatic airway smooth muscle cells. American Journal of Respiratory and Critical Care Medicine. 2006; 174:379-385

Zhong, J, Gencay, M, Bubendorf, L, Burgess, J, Parson, H, Robinson, B, Tamm, M, Black, J, Roth, M. ERK1/2 and p38 MAP kinase control MMP-2, MT1-MMP, and TIMP action and affect cell migration: a comparison between mesothelioma and mesothelial cells. Journal of cellular physiology. 2006; 207:540-52

Oliver, B, Johnston, S, Baraket, M, Burgess, J, King, N, Roth, M, Lim, S, Black, J. Increased proinflammatory responses from asthmatic human airway smooth muscle cells in response to rhinovirus infection. Respiratory research. 2006; 7:71

Johnson, P, Burgess, J, Ge, Q, Poniris, M, Boustany, S, Twigg, S, Black, J. Connective tissue growth factor induces extracellular matrix in asthmatic airway smooth muscle. American journal of respiratory and critical care medicine. 2006; 173:32-41

Burgess, J, Ge, Q, Poniris, M, Boustany, S, Twigg, S, Black, J, Johnson, P. Connective tissue growth factor and vascular endothelial growth factor from airway smooth muscle interact with the extracellular matrix. American journal of physiology. Lung cellular and molecular physiology. 2006; 290:L153-61

2005

Burgess, J. Connective tissue growth factor: A role in airway remodelling in asthma?. Clinical and Experimental Pharmacology and Physiology. 2005; 32:988-994

Black, J, Ge, Q, Boustany, S, Johnson, P, Poniris, M, Glanville, A, Oliver, B, Moir, L, Burgess, J. In vitro studies of lymphangioleiomyomatosis. The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology. 2005; 26:569-76

Burgess, J, Blake, A, Boustany, S, Johnson, P, Armour, C, Black, J, Hunt, N, Hughes, J. CD40 and OX40 ligand are increased on stimulated asthmatic airway smooth muscle. The Journal of allergy and clinical immunology. 2005; 115:302-308

2004

Roth, M, Johnson, P, Borger, P, Bihl, M, Rüdiger, J, King, G, Ge, Q, Hostettler, K, Burgess, J, Black, J, Tamm, M. Dysfunctional interaction of C/EBPalpha and the glucocorticoid receptor in asthmatic bronchial smooth-muscle cells. The New England journal of medicine. 2004; 351:560-74

Hostettler, K, Roth, M, Burgess, J, Johnson, P, Glanville, A, Tamm, M, Black, J, Borger, P. Cyclosporine A mediates fibroproliferation through epithelial cells. Transplantation. 2004; 77:1886-93

Burgess, J, Ge, Q, Boustany, S, Black, J, Johnson, P. Increased sensitivity of asthmatic airway smooth muscle cells to prostaglandin E2 might be mediated by increased numbers of E-prostanoid receptors. The Journal of allergy and clinical immunology. 2004; 113:876-81

Johnson, P, Burgess, J, Underwood, P, Au, W, Poniris, M, Tamm, M, Ge, Q, Roth, M, Black, J. Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autocrine mechanism. The Journal of allergy and clinical immunology. 2004; 113:690-6

Burgess, J, Carlin, S, Pack, R, Arndt, G, Au, W, Johnson, P, Black, J, Hunt, N. Detection and characterization of OX40 ligand expression in human airway smooth muscle cells: a possible role in asthma?. The Journal of allergy and clinical immunology. 2004; 113:683-9

Johnson, P, Burgess, J. Airway smooth muscle and fibroblasts in the pathogenesis of asthma. Current allergy and asthma reports. 2004; 4:102-8

Burgess, J. Overview of Microarrays in Genomic Analysis. In: Molecular Analysis and Genome Discovery. UK: John Wiley & Song, LTD 2004. p. 127-158.

2003

Black, J, Burgess, J, Johnson, P. Airway smooth muscle--its relationship to the extracellular matrix. Respiratory physiology & neurobiology. 2003; 137:339-46

Chambers, L, Black, J, Ge, Q, Carlin, S, Au, W, Poniris, M, Thompson, J, Johnson, P, Burgess, J. PAR-2 activation, PGE2, and COX-2 in human asthmatic and nonasthmatic airway smooth muscle cells. American journal of physiology. Lung cellular and molecular physiology. 2003; 285:L619-27

Burgess, J, Johnson, P, Ge, Q, Au, W, Poniris, M, McParland, B, King, G, Roth, M, Black, J. Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. American journal of respiratory and critical care medicine. 2003; 167:71-7

2002

Roth, M, Johnson, P, Rüdiger, J, King, G, Ge, Q, Burgess, J, Anderson, G, Tamm, M, Black, J. Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. Lancet. 2002; 360:1293-9

Burgess, J, McParland, B. Analysis of gene expression. Methods in enzymology. 2002; 356:259-70

2001

Johnson, P, Roth, M, Tamm, M, Hughes, M, Ge, Q, King, G, Burgess, J, Black, J. Airway smooth muscle cell proliferation is increased in asthma. American journal of respiratory and critical care medicine. 2001; 164:474-7

Burgess, J. Molecular mechanisms of drug-induced thrombocytopenia. Current Opinion In Hematology. 2001; 17(4):375-386

Burgess, J. Gene expression studies using Microarrays. Clinical and Experimental Pharmacology and Physiology. 2001; 103:105-110

2000

Burgess, J, Hazelton, R. New developments in the analysis of gene expression. Redox Report. 2000; 5, Nos 2/3:63-73

Burgess, J, Hazelton, R. New developments in the analysis of gene expression. Redox Report. 2000; 5:63-73

Lehnert, A, Yi, S, Burgess, J, O'Connell, P. Pancreatic islet xenograft tolerance after short-term costimulation blockade is associated with increased CD4+ T cell apoptosis but not immune deviation. Tranplantation. 2000; 69:1176-1185