The University of Sydney
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Dr Jonathon Arnold

E: jonathon.arnold@bosch.org.au
T: +61 2 9036 5361
F: +61 2 9351 7328
D06 - Blackburn Building
The University of Sydney
NSW 2006 Australia

Research interests

Dr Jonathon is an internationally-recognised researcher in the pharmacology of cannabis and the cannabinoids (cannabis-like drugs).

Current national competitive grants

2010

Role of ABC transporters in resistance to antipsychotic therapy and cannabinoid antipsychotic drug interactions
NARSAD Research Support $70,000 over 2 years

Publications

2010

Carson, D, Hunt, G, Guastella, A, Barber, L, Cornish, J, Arnold, J, Boucher, A, McGregor, I. Systemically administered oxytocin decreases methamphetamine activation of the subthalamic nucleus and accumbens core and stimulates oxytocinergic neurons in the hypothalamus. Addiction biology. 2010; :
van Nieuwenhuijzen, P, Long, L, Hunt, G, Arnold, J, McGregor, I. Residual social, memory and oxytocin-related changes in rats following repeated exposure to gamma-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA) or their combination. Psychopharmacology. 2010; :

2009

Gunasekaran, N, Long, L, Dawson, B, Hansen, G, Richardson, D, Li, K, Arnold, J, McGregor, I. Reintoxication: the release of fat-stored Delta(9)-tetrahydrocannabinol (THC) into blood is enhanced by food deprivation or ACTH exposure. British Journal of Pharmacology. 2009; 158:1330-1337
Long, L, Chesworth, R, Huang, X, McGregor, I, Arnold, J, Karl, T. A behavioural comparison of acute and chronic D9-tetrahydrocannabinol and cannabidiol in C57BL/6JArc mice. International Journal of Neuropsychopharmacology. 2009; 0:1-16
Boucher, A, Vivier, L, Metna-Laurent, M, Brayda-Bruno, L, Mons, N, Arnold, J, Micheau, J. Chronic treatment with Delta(9)-tetrahydrocannabinol impairs spatial memory and reduces zif268 expression in the mouse forebrain. Behavioural Pharmacology. 2009; 20:45-55

2008

Jiwane, A, Holland, A, Soundappan, S, Arnold, J. Letters to the editor. Journal of paediatrics and child health. 2008; 44:747-749
Holland, M, Allen, J, Arnold, J. Interaction of plant cannabinoids with the multidrug transporter ABCC1 (MRP1). European journal of pharmacology. 2008; 591:128-31
Quinn, H, Matsumoto, I, Callaghan, P, Long, L, Arnold, J, Gunasekaran, N, Thompson, M, Dawson, B, Mallet, P, Kashem, M, Matsuda-Matsumoto, H, Iwazaki, T, McGregor, I. Adolescent Rats Find Repeated Delta(9)-THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2008; 33:1113-26

2007

Boucher, A, Hunt, G, Karl, T, Micheau, J, McGregor, I, Arnold, J. Heterozygous neuregulin 1 mice display greater baseline and Delta(9)-tetrahydrocannabinol-induced c-Fos expression. Neuroscience. 2007; 149:861-70
McGregor, I, Arnold, J. Cannabis reward: biased towards the fairer sex?. British journal of pharmacology. 2007; 152:562-4
Holland, M, Lau, D, Allen, J, Arnold, J. The multidrug transporter ABCG2 (BCRP) is inhibited by plant-derived cannabinoids. British journal of pharmacology. 2007; 152:815-24
Boucher, A, Arnold, J, Duffy, L, Schofield, P, Micheau, J, Karl, T. Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Delta9-tetrahydrocannabinol. Psychopharmacology. 2007; 192:325-336

2006

Karl, T, Duffy, L, Boucher, A, Arnold, J, Schofield, P. Genetic animal models for neuregulin 1 - valuable tools for schizophrenia research?. Australian and New Zealand Journal of Psychiatry. 2006; 40:A115-A115
Holland, M, Panetta, J, Hoskins, J, Bebawy, M, Roufogalis, B, Allen, J, Arnold, J. The effects of cannabinoids on P-glycoprotein transport and expression in multidrug resistant cells. Biochemical pharmacology. 2006; 71:1146-54

2005

Morley, K, Arnold, J, McGregor, I. Serotonin (1A) receptor involvement in acute 3,4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat. Progress in neuro-psychopharmacology & biological psychiatry. 2005; 29:648-57
Arnold, J. The role of endocannabinoid transmission in cocaine addiction. Pharmacology, biochemistry, and behavior. 2005; 81:396-406

2001

Arnold, J, Hunt, G, McGregor, I. Effects of the cannabinoid receptor agonist CP 55,940 and the cannabinoid receptor antagonist SR 141716 on intracranial self-stimulation in Lewis rats. Life Sciences. 2001; 70:97-108
[Show earlier publications]
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