Dr Bing Yu

E:  bing.yu@bosch.org.au T:  +61 2 9515 5016 F:  +61 2 9550 4017 C39 - Royal Prince Alfred Hospital The University of Sydney NSW 2006 Australia

• Research interests
• Competitive grants
• Publications

Research interests

Current national competitive grants

Publications

2010

Luquin, N, Yu, B, Trent, R, Pamphlett, R. DHPLC can be used to detect low-level mutations in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 2010; 11:76-82

2009

Luquin, N, Yu, B, Saunderson, R, Trent, R, Pamphlett, R. Genetic variants in the promoter of TARDBP in sporadic amyotrophic lateral sclerosis. Neuromuscular Disorders. 2009; 19:696-700

Yu, B. Role of In Silico Tools in Gene Discovery. Molecular biotechnology. 2009; 41:296-306

Morahan, J, Yu, B, Trent, R, Pamphlett, R. A genome-wide analysis of brain DNA methylation identifies new candidate genes for sporadic amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis. 2009; 10:418-429

Trent, R, Yu, B. The future of genetic research in exercise science and sports medicine. Medicine and Sport Science. 2009; 54:187-195

2008

Xiang, J, Li, X, Xu, M, Hong, J, Huang, Y, Tan, J, Lu, X, Dai, M, Yu, B, Ning, G. Zinc Transporter-8 Gene (SLC30A8) Is Associated with Type 2 Diabetes in Chinese. The Journal of clinical endocrinology and metabolism. 2008; 93:4107-12

Luquin, N, Yu, B, Trent, R, Morahan, J, Pamphlett, R. An analysis of the entire SOD1 gene in sporadic ALS. Neuromuscular disorders : NMD. 2008; 18:545-52

Saunderson, R, Yu, B, Trent, R, Pamphlett, R. A comparison of the lengths of androgen receptor triplet repeats in brain and blood in motor neuron diseases. Journal of the neurological sciences. 2008; 267:125-8

Yu, B. In silico gene discovery. Methods in Molecular Medicine. 2008; 141:1-22

Le, H, Hinchcliffe, M, Yu, B, Trent, R. Computer-assisted reading of DNA sequences. Methods in Molecular Medicine. 2008; 141:177-197

2007

Saunderson, R, Yu, B, Trent, R, Pamphlett, R. Low yield in screening patients with sporadic motor neuron disease for Kennedy disease. Internal medicine journal. 2007; 37:772-774

Morahan, J, Yu, B, Trent, R, Pamphlett, R. Genetic susceptibility to environmental toxicants in ALS. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. 2007; 144B:885-90

Morahan, J, Yu, B, Trent, R, Pamphlett, R. A gene-environment study of the paraoxonase 1 gene and pesticides in amyotrophic lateral sclerosis. Neurotoxicology. 2007; 28:532-40

Wang, B, Yu, B, Karim, M, Hu, H, Sun, Y, McGreevy, P, Petocz, P, Held, S, Brand-Miller, J. Dietary sialic acid supplementation improves learning and memory in piglets. The American journal of clinical nutrition. 2007; 85:561-569

Saunderson, R, Yu, B, Trent, R, Pamphlett, R. Are enteroviral receptors different in sporadic motor neuron disease?. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases. 2007; 8:26-30

Morahan, J, Yu, B, Trent, R, Pamphlett, R. Are metallothionein genes silenced in ALS?. Toxicology letters. 2007; 168:83-7

Ma, X, Yu, B, Zhang, Y, Pei, F, Wang, Y, Sun, H, Sun, H. A method of oligochip for single nucleotide polymorphism genotyping in the promoter region of the interleukin-1 beta gene and its clinical application. OLIGONUCLEOTIDES. 2007; 17:336-344

2006

Wu, J, Kar, A, Kuo, D, Yu, B, Havlioglu, N. SRp54 (SFRS11), a regulator for tau exon 10 alternative splicing identified by an expression cloning strategy. Molecular and cellular biology. 2006; 26:6739-47

Gopinath, B, Trent, R, Yu, B. The unique expression profile of the androgen receptor gene in a rat model of neonatal cardiac hypertrophy. Pathology. 2006; 38:142-4

Makris, A, Xu, B, Yu, B, Thornton, C, Hennessy, A. Placental deficiency of interleukin-10 (IL-10) in preeclampsia and its relationship to an IL10 promoter polymorphism. Placenta. 2006; 27:445-451

Makris, A, Xu, B, Yu, B, Thornton, C, Hennessy, A. Placental Deficiency of Interleukin-10 (IL-10) in Preeclampsia and its Relationship to an IL10 Promoter Polymorphism. Placenta. 2006; 27:445-51

Yu, B, Sawyer, N, Chiu, C, Oefner, P, Underhill, P. DNA mutation detection using denaturing high-performance liquid chromatography (Unit 7.10). In: Current Protocols in Human Genetics Volume 2 (Supplement 48). Hoboken, NJ: John Wiley & Sons, Inc. 2006. p. 7.10.1-7.10.14.

Wang, B, Hu, H, Yu, B. Molecular characterization of pig ST8Sia IV--a critical gene for the formation of neural cell adhesion molecule and its response to sialic acid supplement in piglets. Nutritional neuroscience. 2006; 9:147-54

2005

Henderson, J, Withford-Cave, J, Duffy, D, Cole, S, Sawyer, N, Gulbin, J, Hahn, A, Trent, R, Yu, B. The EPAS1 gene influences the aerobic-anaerobic contribution in elite endurance athletes. Human genetics. 2005; 118:416-23

Wang, Y, Ma, X, Sun, S, Sun, Y, Yu, B. Development of an oligochip for genotyping human leukocyte antigen-B51 and its clinical application. Genetic Testing. 2005; 9:292-296

Morahan, J, Yu, B, Trent, R, Pamphlett, R. Screening the metallothionein III gene in sporadic amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis and other motor neuron disorders: official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases. 2005; 6:115-7

Yu, B, Sawyer, N, Caramins, M, Yuan, Z, Saunderson, R, Pamphlett, R, Richmond, D, Jeremy, R, Trent, R. Denaturing high performance liquid chromatography: high throughput mutation screening in familial hypertrophic cardiomyopathy and SNP genotyping in motor neurone disease. Journal of clinical pathology. 2005; 58:479-85

2004

Gopinath, B, Trent, R, Yu, B. Molecular characterisation of neonatal cardiac hypertrophy and its regression. Cardiology in the young. 2004; 14:498-505

Yu, B. What is the value of mutation identification in familial hypertrophic cardiomyopathy?. IUBMB life. 2004; 56:281-3

Trent, R, Yu, B, Caramins, M. Challenges for clinical genetic DNA testing. Expert review of molecular diagnostics. 2004; 4:201-8

Saunderson, R, Yu, B, Trent, R, Pamphlett, R. A polymorphism in the poliovirus receptor gene differs in motor neuron disease. Neuroreport. 2004; 15:383-6

Trent, R, Yu, B, Yu, B. Present and prospective applications of genetic DNA testing (Part II). Chinese Journal of Contemporary Pediatrics. 2004; 6:538-541

Trent, R, Yu, B, Yu, B. Present and prospective applications of genetic DNA testing (Part II). Chinese Journal of Contemporary Pediatrics. 2004; 6:538-541

Trent, R, Yu, B, Caramins, M. Introduction of molecular genetics and genomics into clinical practice. In: Encyclopedia of Diagnostic Genomics and Proteomics. New York, USA: Marcel Dekker, Inc. 2004. p. 676-681.

Trent, R, Yu, B, Caramins, M. Separation techniques ? Capillary electrophoresis. In: Encyclopedia of Diagnostic Genomics and Proteomics. New York, USA: Marcel Dekker, Inc. 2004. p. 210-215.

Trent, R, Yu, B. Present and prospective applications of genetic DNA testing (Part I). Chinese Journal of Contemporary Pediatrics. 2004; 6:447- 450

2003

Wang, B, Staples, A, Hunter, A, Yu, B, Brand Miller, J. Effect of experimental oligosaccharide on brain and body weight. Asia Pacific journal of clinical nutrition.. 2003; 12 Suppl:S60

Orange, S, Painter, D, Horvath, J, Yu, B, Trent, R, Hennessy, A. Placental endothelial nitric oxide synthase localization and expression in normal human pregnancy and pre-eclampsia. Clinical and experimental pharmacology & physiology. 2003; 30:376-81

2002

Brown, L, Singh, L, Sale, K, Yu, B, Trent, R, Fajer, P, Hambly, B. Functional and spectroscopic studies of a familial hypertrophic cardiomyopathy mutation in Motif X of cardiac myosin binding protein-C. European Biophysics Journal With Biophysics Letters. 2002; 31:400-408

2001

Yu, B, Handelsman, D. Pharmacogenetic polymorphisms of the AR and metabolism and susceptibility to hormone-induced azoospermia. The Journal of clinical endocrinology and metabolism. 2001; 86:4406-11

Dedic, J, Weiss, A, Katahira, J, Yu, B, Trent, R, Urbán, Z. A novel elastin gene mutation (1281delC) in a family with supravalvular aortic stenosis: a mutation cluster within exon 20. Human mutation. 2001; 17:81

2000

Trent, R, Le, H, Yu, B, Young, G, Bowden, D. DNA testing for haemochromatosis: diagnostic, predictive and screening implications. Pathology. 2000; 32:274-279

Yu, B. Molecular genetics study of familial hypertrophic cardiomyopathy in Australia. In: Science and Technology Advancing into the New Millennium. China: People's Education Press 2000. p. 27-53.