Associate Professor Karen Waters

• Publications

Publications

2009

Browne, C, Sharma, N, Waters, K, Machaalani, R. The effects of nicotine on the alpha-7 and beta-2 nicotinic acetycholine receptor subunits in the developing piglet brainstem. International Journal of Developmental Neuroscience. 2009; 0:0

Maclean, J, Hayward, P, Fitzgerald, D, Waters, K. Cleft lip and/or palate and breathing during sleep. Sleep medicine reviews. 2009; 13:345-54

Tang, S, Machaalani, R, Kashem, M, Matsumoto, I, Waters, K. Intermittent Hypercapnic Hypoxia Induced Protein Changes in the Piglet Hippocampus Identified by MALDI-TOF-MS. Neurochemical Research. 2009; 34:2215-2225

Maclean, J, Waters, K, Fitzsimons, D, Hayward, P, Fitzgerald, D. Screening for obstructive sleep apnea in preschool children with cleft palate. The Cleft palate-craniofacial journal. 2009; 46:117-123

Machaalani, R, Say, M, Waters, K. Serotoninergic receptor 1A in the sudden infant death syndrome brainstem medulla and associations with clinical risk factors. Acta neuropathologica. 2009; 117:257-65

Waters, K, Cheng, A. Adenotonsillectomy in the context of obstructive sleep apnoea. Paediatric Respiratory Reviews. 2009; 10:25-31

2008

Tang, S, Machaalani, R, Waters, K. Brain-derived neurotrophic factor (BDNF) and TrkB in the piglet brainstem after post-natal nicotine and intermittent hypercapnic hypoxia. Brain research. 2008; 1232:195-205

Waters, K. Interventions in the paediatric sleep laboratory: the use and titration of respiratory support therapies. Paediatric respiratory reviews. 2008; 9:181-191

Robinson, P, Waters, K. Are children just small adults? The differences between paediatric and adult sleep medicine. Internal medicine journal. 2008; 38:719-31

Aouad, L, Tam, K, Waters, K. Effects of acute intermittent hypercapnic hypoxia on insulin sensitivity in piglets using euglycemic clamp. Metabolism: clinical and experimental. 2008; 57:1056-1063

MacLean, J, Fitzsimons, D, Hayward, P, Waters, K, Fitzgerald, D. The identification of children with cleft palate and sleep disordered breathing using a referral system. Pediatric pulmonology. 2008; 43:245-250

Machaalani, R, Waters, K. Neuronal cell death in the Sudden Infant Death Syndrome brainstem and associations with risk factors. Brain. 2008; 131:218-228

2007

Waters, K, Mast, B, Vella, S, De La Eva, R, O'Brien, L, Bailey, S, Tam, C, Wong, M, Baur, L. Structural equation modeling of sleep apnea, inflammation, and metabolic dysfunction in children. Journal of sleep research. 2007; 16:388-395

Machaalani, R, Radford, J, Waters, K. Tissue fixation effects on immunohistochemical staining of caspase-3 in brain tissue. Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry. 2007; 15:463-470

Machaalani, R, Arlotto, M, Waters, K, Gozal, E, Berger, F, Dematteis, M. A Novel Method of Tissue Collection and Storage: Validation Using SELDI-TOF MS Analysis. Clinical chemistry. 2007; 53:1387-1389

Say, M, Machaalani, R, Waters, K. Changes in serotoninergic receptors 1A and 2A in the piglet brainstem after intermittent hypercapnic hypoxia (IHH) and nicotine. Brain research. 2007; 1152:17-26

Tam, C, Wong, M, Tam, K, Aouad, L, Waters, K. The effect of acute intermittent hypercapnic hypoxia treatment on IL-6, TNF-alpha, and CRP levels in piglets. Sleep. 2007; 30:723-727

Machaalani, R, Rodriguez, M, Waters, K. Active caspase-3 in the sudden infant death syndrome (SIDS) brainstem. Acta neuropathologica. 2007; 113:577-584

Young, H, Lowe, A, Fitzgerald, D, Seton, C, Waters, K, Kenny, E, Hynan, L, Iannaccone, S, North, K, Ryan, M. Outcome of noninvasive ventilation in children with neuromuscular disease. Neurology. 2007; 68:198-201

2006

Fanous, A, Machaalani, R, Waters, K. N-methyl-d-aspartate receptor 1 changes in the piglet brainstem after nicotine and/or intermittent hypercapnic-hypoxia. Neuroscience. 2006; 142:401-9

Machaalani, R, Waters, K. Postnatal nicotine and/or intermittent hypercapnic hypoxia effects on apoptotic markers in the developing piglet brainstem medulla. Neuroscience. 2006; 142:107-17

O'Brien, L, Sitha, S, Baur, L, Waters, K. Obesity increases the risk for persisting obstructive sleep apnea after treatment in children. International Journal of Pediatric Otorhinolaryngology. 2006; 70:1555-1560

Waters, K, Sitha, S, O'brien, L, Bibby, S, de Torres, C, Vella, S, de la Eva, R. Follow-up on Metabolic Markers in Children Treated for Obstructive Sleep Apnea. American journal of respiratory and critical care medicine. 2006; 174:455-60

Tam, C, Wong, M, McBain, R, Bailey, S, Waters, K. Inflammatory measures in children with obstructive sleep apnoea. Journal of paediatrics and child health. 2006; 42:277-82

2005

Waters, K, Machaalani, R. Role of NMDA receptors in development of respiratory control. Respiratory physiology & neurobiology. 2005; 149:123-30

Waters, K, Tinworth, K. Habituation of arousal responses after intermittent hypercapnic hypoxia in piglets. American journal of respiratory and critical care medicine. 2005; 171:1305-11

Kennedy, J, Waters, K. 8. Investigation and treatment of upper-airway obstruction: childhood sleep disorders I. Medical Journal of Australia. 2005; 182:419-23

Kennedy, J, Waters, K. Investigation and treatment of upper-airway obstruction: childhood sleep disorders I. Medical Journal of Australia. 2005; 182:419-423

Machaalani, R, Waters, K, Tinworth, K. Effects of postnatal nicotine exposure on apoptotic markers in the developing piglet brain. Neuroscience. 2005; 132:325-33

2004

Peiris, T, Machaalani, R, Waters, K. Brain-derived neurotrophic factor mRNA and protein in the piglet brainstem and effects of Intermittent Hypercapnic Hypoxia. Brain research. 2004; 1029:11-23

Waters, K, Gozal, D. Developmental and metabolic implications of the hypoxic ventilatory response. Paediatric respiratory reviews. 2004; 5:173-81

Yates, K, Festa, M, Gillis, J, Waters, K, North, K. Outcome of children with neuromuscular disease admitted to paediatric intensive care. Archives of disease in childhood. 2004; 89:170-5

Waters, K. Cytokines in sudden infant death syndrome. Lancet. Neurology. 2004; 3:81

Waters, K, Machaalani, R. NMDA receptors in the developing brain and effects of noxious insults. Neuro-Signals. 2004; 13:162-74

2003

Machaalani, R, Waters, K. NMDA receptor 1 expression in the brainstem of human infants and its relevance to the sudden infant death syndrome (SIDS). Journal of neuropathology and experimental neurology. 2003; 62:1076-1085

Machaalani, R, Waters, K. Increased neuronal cell death after intermittent hypercapnic hypoxia in the developing piglet brainstem. Brain research. 2003; 985:127-134

Waters, K, Gozal, D. Responses to hypoxia during early development. Respiratory physiology & neurobiology. 2003; 136:115-29

Machaalani, R, Waters, K. Correlations between brainstem NMDA receptor changes and active neuronal cell death after intermittent hypercapnic hypoxia in the developing piglet. Brain research. 2003; 975:141-8

Waters, K, Tinworth, K. Effect of stimulus cycle time on acute respiratory responses to intermittent hypercapnic hypoxia in unsedated piglets. Journal of applied physiology (Bethesda, Md. : 1985). 2003; 94:2465-74

Don, G, Waters, K. Influence of sleep state on frequency of swallowing, apnea, and arousal in human infants. Journal of applied physiology (Bethesda, Md. : 1985). 2003; 94:2456-64

2002

de la Eva, R, Baur, L, Donaghue, K, Waters, K. Metabolic correlates with obstructive sleep apnea in obese subjects. The Journal of pediatrics. 2002; 140:654-9

Machaalani, R, Waters, K. Distribution and quantification of NMDA R1 and mRNA and protein in the piglet brainstem and effects of intermittent hypercapnic hopoxia (IHH). Brain Research. 2002; 951:293-300

Waters, K, McBrien, F, Stewart, P, Hinder, M, Wharton, S. Effects of OSA, inhalational anesthesia, and fentanyl on the airway and ventilation of children. Journal Of Applied Physiology. 2002; 92:1987-1994

Reyes, L, Tinworth, K, Li, K, Yau, D, Waters, K. Observer-blinded comparison of two nonopioid analgesics for postoperative pain in piglets. Pharmacology, Biochemistry and Behavior. 2002; 73:521-528

Relf, B, Machaalani, R, Waters, K. Retrieval of mRNA from paraffin-embedded human infant brain tissue for non-radioactive in situ hybridization using oligonucleotides. Journal Of Neuroscience Methods. 2002; 115:129-136

2001

Waters, K, Tinworth, K. Depression of ventilatory responses after daily, cyclic hypercapnic hypoxia in piglets. Journal of applied physiology (Bethesda, Md. : 1985). 2001; 90:1065-73

2000

Brouillette, R, Morielli, A, Leimanis, A, Waters, K, Luciano, R, Ducharme, F. Nocturnal pulse oximetry as an abbreviated testing modality for pediatric obstructive sleep apnea. Pediatrics. 2000; 105:405-412

Don, G, Kirjavainen, T, Broome, C, Seton, C, Waters, K. Site and mechanics of spontaneous, sleep-associated obstructive apnea in infants. Journal of Applied Physiology. 2000; 89:2453-2462

Kirk, V, Morielli, A, Gozal, D, Marcus, C, Waters, K, D'Andrea, L, Rosen, C, Deray, M, Brouillette, R. Treatment of sleep-disordered breathing in children with myelomeningocele. Pediatric Pulmonology. 2000; 30:445-452